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Diclazuril is a broad-spectrum anticoccidial agent belonging to the benzeneacetonitrile chemical class. It is primarily used in veterinary medicine to prevent and treat coccidiosis in livestock (specifically lambs and calves) and equine protozoal myeloencephalitis (EPM) in horses -2-4.
Chemical Name: (±)-2,6-dichloro-α-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)benzeneacetonitrile -4.
Molecular Formula: C~17~H~9~Cl~3~N~4~O~2~ -4.
Molecular Weight: 407.64 g/mol -4.
Appearance: White to off-white powder or oral suspension
Diclazuril is widely used across multiple animal species for the prevention and treatment of protozoal infections.
4. Specification
| Tests | Item | Acceptance criteria |
| Characters | Appearance | Almost white or pale yellow powder; practically odorless |
| Solubility | Sparingly soluble in dimethylformamide, slightly soluble in tetrahydrofuran, practically insoluble in water and ethanol. | |
| Identification | UV spectrum | maximum absorption at 220nm and 277nm. |
| IR spectrum | conforms to that of CRS | |
| Related substances | The total impurities should be NMT 2.5% calculated with peak area normalization method except the solvent peak. | |
| Loss on drying | ≤ 0.5 % (105℃) | |
| Residue on ignirion | ≤ 0.1 % | |
| Heavy metals | ≤20ppm | |
| Assay | NLT96.0 % (dry product) |
